Characterization of neurotransmitter receptor-mediated information transduction

The development of novel drugs capable to prevent cell adhesion mediated by integrins


Early life events have been implicated in the programming of adult chronic diseases


Regulation of neuronal and non-neuronal gene transcription by transcription factors or extracellular signalling molecules.


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Welcome to the Molecular and Cellular Pharmacology unit of the Department of Pharmacy and Biotechnology-University of Bologna

Signal transduction is the process by which signals outside of the cells, such as hormones, sensory inputs, growth factors, and neurotransmitters coordinate and regulate the physiology of individual cells. Coordinated interactions between cells in the body is critical to the development and proper functioning of multicellular organisms. In humans, disregulation of these pathways can contribute to diseases such as cancer, neurological degeneration, and cardiovascular disease. Research in this area spans a spectrum of disciplines including studies on the individual molecules involved in recognition of the signal (receptors), studies on the individual molecules that help to convert the signal into cellular changes, and how these interactions result in changes in the physiology and proper functioning of cells and multicellular organisms. Understanding at all of these levels is required for a complete picture of cellular regulation and disease


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